GenoStat is a forensic DNA analysis java-based application that generates DNA profile match statistics (RMP, CPI and things like sibling match probabilities)
as well performing mixture resolution (separating mixtures into their contributor components).
We're hoping that most of what GenoStat does is self-explanatory (at least to people confronted with DNA testing results).
You should be able to just double-click on it to get it to run (if you have Java installed on your computer).
With this version you'll need to type in RFU values for any alleles at any loci that you want to consider in your analysis.
If you type in values for three or four alleles at any locus it will presume that you are dealing with a two-person mixture
and will attempt to deconvolve it for you. If you type in more than four alleles at a locus it will warn you that it can
only deconvolve two-person mixtures but will still generate CPI statistics for you. You'll see you can change the value
for theta and can pick from allele frequencies from one of three different databases. You can see what effect
deleting any locus or loci from consideration just by clicking on some check boxes and quickly get an answer for a
variety of different kinds of match probabilities (unrelated through sibling to second cousin) with a drop down menu.
We've tested it on Macs, PCs, and Linux boxes on our end.
This release is shareware and we would be happy if you distributed it freely.
You'll always be able to get the most up to date version of
GenoStat directly off this web page.
GenoStat has been a not very well-kept secret at Forensic Bioinformatics for the past several months.
We're excited about it and very much hope that you find it useful and get excited about it too.
We'd very much like to hear any suggestions you might have for improvements.
Please treat this beta release as roughly as you can and tell us if you find it making errors of any kind.
Basic statistics mode: enter DNA profiles by simply clicking allele checkboxes.
Mixture resolution statistics can now take into account allelic dropout.
Full report generation.
Full support for Profiler Plus, COfiler, Identifiler, PowerPlex16, and SGM+ testing kits.
Import Genophiler results: avoid entering profiles by simply inserting your Genophiler CD and selecting the samples you want.
Calculate statistics with loci containing specified allelic dropout.
Import additional allele frequency databases.
Option to include or exclude CPI calculation from printed report.
Option to incorporate theta correction into heterozygotes AND homozygotes or homozygotes only.
Option to utilize a magnitude-specific peak height ratio threshold.
International computer support.
Current version: May 11, 2009
Internet Explorer users: The basic version of GenoStat without extra databases (GenoStat.jar) may be automatically renamed as GenoStat.zip. Please rename as GenoStat.jar to run.