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Forensic Bioinformatics

9th Annual Conference
Forensic DNA in the Courtroom

August 12, 2010: St. Croix
August 13, 2010: St. Thomas
U.S. Virgin Islands


About the seminar

Dan Krane and Keith Inman will be presenting a full-day DNA workshop in St. Croix and St. Thomas (U.S. Virgin Islands). The workshop is an opportunity for attorneys of all experience levels to learn about the implications pertaining to forensic DNA profiling results. The seminar will cover subjects germane to forensic DNA including: evidence collection, quality assurance, validation of laboratory procedures, serology, transfer, identification, technical artifacts and error, DNA database searches, juror comprehension, expert witness selection, and due diligence. The workshop will also include a hands-on component to familiarize the participants with the processes involved with forensic DNA profiling. Course materials consisting of speaker presentations and supporting references such as key literature, legal documents and web sites will be provided to each participant in electronic format at the beginning of the seminar. There are no admission restrictions.


Course speakers

Dan Krane, Ph.D., graduated with a Bachelor's degree for a double major in Biology and Chemistry from John Carroll University in 1985 and a Ph.D. in Molecular Biology from Penn State University in 1990. From there he did post-doctoral research at Washington University and Harvard before accepting a faculty appointment at Wright State University in 1993. His research interests are primarily in the areas of molecular evolution and the way that gene frequencies change over the course of time in populations of organisms. He has published more than 40 scholarly papers in a variety of topics including population genetic studies of the genetic diversity of human populations at DNA typing loci, of organisms exposed to environmental stressors, and the use of DNA typing in forensic science. Dan is also the lead author of a widely-used undergraduate textbook, Fundamental Concepts of Bioinformatics. Dan is a member of the Commonwealth of Virginia's Scientific Advisory Committee, a 12-member panel established by statute to provide oversight and guidance to the Virginia Department of Forensic Science (the crime laboratory for the Commonwealth of Virginia). Since 1991, Dan has testified in over 75 criminal proceedings that have involved forensic DNA typing (in 22 different states and in three different Federal courts within the United States, a Coronial Inquest in the State of Victoria in Australia, the Belfast Crown Court in Northern Ireland, and the Oxford Crown Court in England). dan.krane@wright.edu

Keith Inman holds a B.S. and M.Crim., both from the University of California at Berkeley. In his professional career he has been employed as a criminalist by the Orange County Sheriff's Department, the Los Angeles County Sheriff's Department, the Los Angeles County Chief Medical Examiner-Coroner, the Oakland Police Department, and most recently the California State Department of Justice DNA Laboratory. He also previously worked in private practice for six years, undertaking both prosecution and defense work. He has co-authored An Introduction to Forensic DNA Analysis, a book that has become the preeminent reference for both attorneys and crime laboratories, and The Principles and Practice of Criminalistics, a book aimed at practicing criminalists. He teaches a variety of classes in the Criminal Justice Administration Department at California State University, East Bay, including Basic and Advanced Criminal Investigation, Criminal Identification, Crime Prevention and Control, and Ethics. kinman@forensica.com


Location

The workshop will be located at the court houses in St. Croix and St. Thomas.

Jury Assembly Room
Superior Court of the Virgin Islands
Division of St. Croix

Jury Assembly Room
Superior Court of the Virgin Islands
Division of St. Thomas


Continuing Legal Education Credit

Continuing Legal Education (CLE) credit is available from the Virgin Islands (6 credits), Florida (8 credits), Georgia (6.83), and Ohio (6.75 credits).

CLE credit may be available from other states upon request.


Schedule

9:00 - 9:15 : Introduction to DNA testing
9:15 - 9:35 : Evolution of DNA testing technology
9:35 - 10:20 : Automated STR DNA testing
10:20 - 10:30 : Break
10:30 - 11:00 : Basic DNA statistics
11:00 - 11:20 : Parentage testing
11:20 - 11:45 : Documenting laboratory errors
11:45 - 12:30 : Lunch (on your own)
12:30 - 1:00 : Opportunities for subjective interpretation
1:00 - 1:30 : Observer effects/blind testing
1:30 - 2:15 : Mixture interpretation
2:15 - 2:30 : Break
2:30 - 3:00 : Limits of detection and quantitation
3:00 - 3:30 : Familial searching
3:30 - 3:45 : Cold Hit statistics
3:45 - 3:55 : DNA transfer
3:55 - 4:30 : Low Copy Number (LCN) DNA testing
4:30 - 4:45 : Degraded samples and the Victoria Coroner's inquest into the death of Jaidyn Leskie
4:45 - 5:00 : Steps in preparing a DNA case


Registration

Prior to July 28th: $295

After July 28th: $325

You may submit payment by mailing a check or by using a credit card through PayPal.

Date
Download the registration form here.



Course materials

  • Presentation: The main presentation given by Dan Krane and Keith Inman


  • W Thompson, S Ford, T Doom, M Raymer, and D Krane. Evaluating forensic DNA evidence: Essential elements of a competent defense review. Part 1. The Champion. 27(3):16-25, April 2003.

  • W Thompson, S Ford, T Doom, M Raymer, and D Krane. Evaluating forensic DNA evidence: Essential elements of a competent defense review. Part 2. The Champion. 27(4):24-28, May 2003.

  • Useful chart of DNA terms, information on commonly-used testing kits, how to identify some specific problems with DNA evidence, and twelve important questions that always need to be asked about DNA evidence.

  • William Thompson and Dan Krane. Chapter 11: DNA in the courtroom. Psychological and Scientific Evidence in Criminal Trials. West Group. 2003.

  • William C. Thompson. Tarnish on the 'gold standard:' Understanding recent problems in forensic DNA testing. The Champion. 30(1):10-16, January/February 2006.

  • William A. Tobin and William C. Thompson. Evaluating and challenging forensic identification evidence. The Champion. 30(6):12-21, July 2006.

  • National Research Council. Strengthening Forensic Science in the United States: A Path Forward. Washington DC, National Academy Press: 2009. (On-line)

  • National Research Council. The Evaluation of Forensic DNA Evidence. Washington DC, National Academy Press: 1996. (On-line)

  • National Research Council. DNA Technology in Forensic Science. Washington DC, National Academy Press: 1992. (On-line)

  • D.E. Krane, V. Bahn, D. Balding, B. Barlow, H. Cash, B.L. Desportes, P. D’Eustachio, K. Devlin, T.E. Doom, I. Dror, S. Ford, C. Funk, J. Gilder, G. Hampikian, K. Inman, A. Jamieson, P.E. Kent, R. Koppl, I. Kornfield, S. Krimsky, J. Mnookin, L. Mueller, E. Murphy, D.R. Paoletti, D.A. Petrov, M. Raymer, D.M. Risinger, A. Roth, N. Rudin, W. Shields, J.A. Siegel, M. Slatkin, Y.S. Song, T. Speed, C. Spiegelman, P. Sullivan, A.R. Swienton, T. Tarpey, W.C. Thompson, E. Ungvarsky, S. Zabell. Time for DNA disclosure. Science. 2009;326:1631-1632.

  • D. Krane, S. Ford, J. Gilder, K. Inman, A. Jamieson, R. Koppl, I. Kornfield, D. Risinger, N. Rudin, M. Taylor, W.C. Thompson. Sequential unmasking: A means of minimizing observer effects in forensic DNA interpretation. Journal of Forensic Sciences. 2008;53(4):1006-7. Response - Author's Response

  • J. Gilder, R. Koppl, I. Kornfield, D. Krane, L. Mueller, W.C. Thompson. Comments on the review of low copy number testing. International Journal of Legal Medicine. 2009. Pre-print

  • B. Budowle, A.J. Eisenberg, A. van Daal. Validity of low copy number typing and applications to forensic science. Croatian Medical Journal. 2009;50(3):207-217.

  • B. Caddy, G.R. Taylor, and A.M.T. Linacre. A Review of the Science of Low Template DNA Analysis. April 2008.

  • Justice Weir. The Queen v. Sean Hoey. Crown Court sitting in Northern Ireland. Bill No: 341/05. Neutral citation no. [2007] NICC 49. Ref: WEI7021. December 20, 2007.

  • J. Gilder, T. Doom, K. Inman, and D. Krane. Run-specific limits of detection and quantitation for STR-based DNA testing. Journal of Forensic Sciences. 2007;52(1):97-101.

  • Keith Devlin. Scientific heat about cold hits. Unfinished draft. 2007.

  • F.R. Bieber, C.H. Brenner, D. Lazer. Finding criminals through DNA of their relatives. Science. 2006; 312:1315-1316.

  • D. Paoletti, T. Doom, M. Raymer, and D. Krane. Assessing the implications for close relatives in the event of similar but non-matching DNA profiles. Jurimetrics. 2006;46(2):161-175.

  • C. Rowland, R. Van Trees, M. Taylor, and D. Krane. Was the Shawnee war chief Blue Jacket a Caucasian? The Ohio Journal of Science. 2006;106(4):126-129.

  • Inquest into the death of Jaidyn Raymond Leskie   Coroners Case Number: 007/98. October 2006.

  • Dan E. Krane. Victoria State Coroner's Inquest into the Death of Jaidyn Leskie. DNA report. December 4, 2003.

  • D. Paoletti, T. Doom, C. Krane, M. Raymer, and D. Krane. Empirical analysis of the STR profiles resulting from conceptual mixtures. Journal of Forensic Sciences. 2005;50(6):1361-1366.

  • J. Gilder, S. Ford, T. Doom, M. Raymer, and D. Krane. Systematic differences in electropherogram peak heights reported by different version of the GeneScan® software. Journal of Forensic Sciences. 2004;49(1):85-92.

  • D. Risinger and M. Saks. A house with no foundation: forensic science needs to build a base of rigerous research to establish its reliability. Issues in Science and Technology. Fall 2003.

  • A. Nance and S. Morris. Jury Understanding of DNA Evidence: An Empirical Assessment of Presentation Formats for Trace Evidence with a Relatively Small Random Match Probability. October 17, 2003.

  • M. Taylor and E. Johnson. TA case #1458, Commonwealth v. Dirk K. Geineder. Mixture studies report.

  • E. Kafarowski, A. Lyon, and M. Sloan. The retention and transfer of spermatozoa in clothing by machine washing. Canadian Society of Forensic Science Journal, 20(1):7.11, 1996.

  • Stanley Sawyer, Ann Podleski, Dan Krane, and Daniel Hartl. DNA Fingerprinting Loci Do Show Population Differences: Comments on Budlowe et al. American Journal of Human Genetics. 1996;59:272-274.

  • Ronald Ostrowski and Dan E. Krane. Unresolved Issues in the Forensic Use of DNA Profiling. Accountability in Research. 1993;3:47-54.

  • Dan E. Krane, Robert W. Allen, Stanley A. Sawyer, Dmitri A. Petrov, and Daniel L. Hartl. Genetic Differences at Four DNA Typing Loci in Finnish, Italian, and Mixed Caucasian Populations. Proceedings of the National Academy of Sciences - USA (Genetics). 1992;89:10583-10587.

    Paternity materials

  • Elston, R.C. (1986). Probability and paternity testing. American Journal of Human Genetics. 39: 112-122.

  • Kaiser, L. and Sever, G. (1983). Paternity testing: I. Calculation of paternity indexes. American Journal of Medical Genetics. 15(2): 323-329.

  • Lee, C.L. (1979). Numerical expression of paternity test results using predetermined indexes. American Journal of Clinical Pathologists. 73(4).

  • Li, C.C. and Chakravarti, A. (1985). Basic fallacies in the formulation of the patrenity index. American Journal of Human Genetics. 37(4): 809-818.

  • Morris, J., Sandra, A.I., and Glassberg, J. (1989). Biostatistical evaluation of evidence from continuous allele frequency distribution deoxyribonucleic acid (DNA) probes in reference to disputed paternity and identity. Journal of Forensic Sciences, JFSCA, 34(6): 1311-1317.

  • Morris, J. (1989). Experimental validation of paternity probability (to the editor). Transfusion, 29(3): 281.

  • Morris, J. (1989). Limitations of paternity testing calculations revisited (to the editor). Transfusion, 29(3): 280.

  • Thomson, J.A., Pilotti, V.,Stevens, P., Ayres, K.L., and Debenham, P.G. (1999). Validation of short tandem repeat analysis for the investigation of cases of disputed paternity. Forensic Science International. 100: 1–16.

  • Xiang, H.L., Tai, S.L., Karenda, F.N.N., and Wang, J. (2002). Deduction of paternity index from DNA mixture. Forensic Science International. 128: 105–107.

  • Zabell, S. (2003). A paternity paradox. Conference on Statistics and DNA Profiling, August 29-30, 2003.



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    Last modified: 07/30/10