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Familial searches: what constitutes probable cause when a database search finds someone similar to but different from an evidence sample? (Dr. Dan Krane, Wright State University)

A perfect match between the STR DNA profile of an evidence sample and an individual whose genotype is maintained in a database of convicted offenders has clear utility as an investigative tool. Lack of concordance between the alleles of an evidence sample and an individual's DNA profile is also commonly used as an investigative tool in that the individual can be excluded as a source of the biological material in the evidence sample. Very similar but nonetheless non-matching DNA profiles between an evidence sample and an individual whose STR genotype is available also have the potential to provide law enforcement investigators useful information by suggesting that a close relative of the individual may be the actual source of the evidence sample.

Materials

Presentation

Bieber FR, Brenner CH, Lazer D. Finding criminals through DNA of their relatives. Science. 2006; 312:1315-1316.

Federal Bureau of Investigation (FBI). Interim plan for the release of information in the event of a "partial match" at NDIS. Combined DNA Index System (CODIS) Bulletin. July 20, 2006.

Paoletti D, Doom T, Raymer M, Krane D. Assessing the implications for close relatives in the event of similar but non-matching DNA profiles. Jurimetrics. 2006; 46(2):161-175.

Using a relative's DNA to catch criminals. Scott Michels. US News and World Report. August 3, 2006.